diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 7b9daec10b..162c4237e1 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -14597,13 +14597,14 @@ Needleman-Wunsch).")
     (build-system pyproject-build-system)
     (arguments
      (list
+      #:tests? #f ;no tests
       #:phases
       '(modify-phases %standard-phases
          (add-after 'unpack 'chdir
            (lambda _ (chdir "pairadise")))
          (add-before 'build '2to3
            (lambda _ (invoke "2to3" "--write" "--nobackups" "."))))))
-    (native-inputs (list python-setuptools python-wheel))
+    (native-inputs (list python-setuptools))
     (inputs (list star))
     (propagated-inputs (list python-pysam))
     (home-page "https://github.com/Xinglab/PAIRADISE")