diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 6f4c99a7ece..41f893e817c 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -9767,6 +9767,7 @@ generally slower than modern maximum likelihood approaches.")
      (list bc
            time
            python-wrapper
+           python-setuptools
            pkg-config))
     (inputs
      (list htslib))