diff --git a/gnu/packages/mpi.scm b/gnu/packages/mpi.scm
index a9411f922e..4aaf2d5ed7 100644
--- a/gnu/packages/mpi.scm
+++ b/gnu/packages/mpi.scm
@@ -38,6 +38,7 @@
   #:use-module (guix build-system gnu)
   #:use-module (guix build-system pyproject)
   #:use-module (gnu packages)
+  #:use-module (gnu packages autotools)
   #:use-module (gnu packages base)
   #:use-module (gnu packages bash)
   #:use-module (gnu packages bison)
@@ -171,20 +172,33 @@ bind processes, and much more.")
                                   "/hwloc-" version ".tar.bz2"))
               (sha256
                (base32
-                "1aqdznqp7f18yg95vbr5n6ccxxdiywacygvn3wbhzn7bnspkdsaj"))))
+                "1aqdznqp7f18yg95vbr5n6ccxxdiywacygvn3wbhzn7bnspkdsaj"))
+              ;; XXX: Remove after updating package from 2.13.0.
+              (patches (search-patches "hwloc-add-with-opencl.patch"))))
 
     (native-inputs (modify-inputs (package-native-inputs hwloc-1)
+                     (append autoconf)
+                     (append automake)
+                     (append libtool)
                      (append opencl-headers)
-                     (append opencl-icd-loader)
                      (append bash)))              ;for completion tests
     (inputs (modify-inputs (package-inputs hwloc-1)
               (append level-zero)
               (append libxml2)
+              (append opencl-icd-loader)
               (delete "numactl")))               ;libnuma is no longer needed.
     (arguments
      (substitute-keyword-arguments (package-arguments hwloc-1)
+       ((#:configure-flags flags '())
+        #~(cons* (string-append "--with-opencl="
+                                #$(this-package-input "opencl-icd-loader"))
+                 #$flags))
        ((#:phases phases)
         #~(modify-phases #$phases
+            (add-after 'unpack 'delete-configure
+              (lambda _
+                ;; Remove configure file to generate it with patch.
+                (delete-file "configure")))
             (replace 'skip-linux-libnuma-test
               (lambda _
                 ;; Arrange to skip 'tests/hwloc/linux-libnuma', which fails on
diff --git a/gnu/packages/patches/hwloc-add-with-opencl.patch b/gnu/packages/patches/hwloc-add-with-opencl.patch
new file mode 100644
index 0000000000..03a16d34d0
--- /dev/null
+++ b/gnu/packages/patches/hwloc-add-with-opencl.patch
@@ -0,0 +1,90 @@
+From f30cc463a948260088b496c3609dd91c83c0ce1b Mon Sep 17 00:00:00 2001
+From: Brice Goglin <Brice.Goglin@inria.fr>
+Date: Mon, 16 Feb 2026 15:00:53 +0100
+Subject: [PATCH] configure: add --with-opencl=<dir>
+
+For non-ROCm non-CUDA installs.
+
+Thanks to Romain Garbage for the suggestion.
+
+Signed-off-by: Brice Goglin <Brice.Goglin@inria.fr>
+(cherry picked from commit 462eff5a4541dfcb3db15034490c796c4f1d8ec6)
+---
+ config/hwloc.m4          | 18 +++++++++++++++---
+ config/hwloc_internal.m4 | 13 ++++++++++++-
+ 2 files changed, 27 insertions(+), 4 deletions(-)
+
+diff --git a/config/hwloc.m4 b/config/hwloc.m4
+index e0057e8e5..4a26a7ec0 100644
+--- a/config/hwloc.m4
++++ b/config/hwloc.m4
+@@ -1,7 +1,7 @@
+ dnl -*- Autoconf -*-
+ dnl
+ dnl SPDX-License-Identifier: BSD-3-Clause
+-dnl Copyright © 2009-2025 Inria.  All rights reserved.
++dnl Copyright © 2009-2026 Inria.  All rights reserved.
+ dnl Copyright © 2009-2012, 2015-2017, 2020, 2023, 2025 Université Bordeaux
+ dnl Copyright © 2004-2005 The Trustees of Indiana University and Indiana
+ dnl                         University Research and Technology
+@@ -1365,6 +1365,18 @@ return rsmi_init(0);
+       echo "**** OpenCL configuration"
+ 
+       hwloc_opencl_happy=yes
++
++      if test "x$with_opencl" != x -a "x$with_opencl" != xyes; then
++        opencl_dir=$with_opencl
++        AC_MSG_NOTICE([using custom OpenCL install path $opencl_dir ...])
++      else
++        AC_MSG_NOTICE([assuming OpenCL is installed in standard directories ...])
++      fi
++      if test "x$opencl_dir" != x; then
++        HWLOC_OPENCL_CPPFLAGS="-I$opencl_dir/include/"
++        HWLOC_OPENCL_LDFLAGS="-L$opencl_dir/lib/"
++      fi
++
+       case ${target} in
+       *-*-darwin*)
+         # On Darwin, only use the OpenCL framework
+@@ -1387,8 +1399,8 @@ return clGetDeviceIDs(0, 0, 0, NULL, NULL);
+       ;;
+       *)
+         # On Others, look for OpenCL at normal locations
+-        HWLOC_OPENCL_CPPFLAGS="$HWLOC_CUDA_COMMON_CPPFLAGS"
+-        HWLOC_OPENCL_LDFLAGS="$HWLOC_CUDA_COMMON_LDFLAGS"
++        HWLOC_OPENCL_CPPFLAGS="$HWLOC_OPENCL_CPPFLAGS $HWLOC_CUDA_COMMON_CPPFLAGS"
++        HWLOC_OPENCL_LDFLAGS="$HWLOC_OPENCL_LDFLAGS $HWLOC_CUDA_COMMON_LDFLAGS"
+         if test "x$rocm_dir" != x; then
+ 	   if test -d "$rocm_dir/include/CL"; then
+              HWLOC_OPENCL_CPPFLAGS="$HWLOC_OPENCL_CPPFLAGS -I$rocm_dir/include/"
+diff --git a/config/hwloc_internal.m4 b/config/hwloc_internal.m4
+index da6505e91..1135a245f 100644
+--- a/config/hwloc_internal.m4
++++ b/config/hwloc_internal.m4
+@@ -1,7 +1,7 @@
+ dnl -*- Autoconf -*-
+ dnl
+ dnl SPDX-License-Identifier: BSD-3-Clause
+-dnl Copyright © 2010-2025 Inria.  All rights reserved.
++dnl Copyright © 2010-2026 Inria.  All rights reserved.
+ dnl Copyright © 2009, 2011 Université Bordeaux
+ dnl Copyright © 2004-2005 The Trustees of Indiana University and Indiana
+ dnl                         University Research and Technology
+@@ -147,6 +147,17 @@ AC_DEFUN([HWLOC_DEFINE_ARGS],[
+ 		       [AC_MSG_ERROR([--with-amdgpu=<dir> missing the installation directory])])]
+ 		)
+ 
++    # OpenCL
++    AC_ARG_ENABLE([opencl],
++                  AS_HELP_STRING([--disable-opencl],
++                                 [Disable the OpenCL device discovery]))
++    AC_ARG_WITH([opencl],
++                AS_HELP_STRING([--with-opencl=<dir>],
++		               [Specify the OpenCL installation directory]),
++		[AS_IF([test "x$withval" = xyes -o "x$withval" = x],
++		       [AC_MSG_ERROR([--with-opencl=<dir> missing the installation directory])])]
++		)
++
+     # LevelZero
+     AC_ARG_ENABLE([levelzero],
+                   AS_HELP_STRING([--disable-levelzero],